Asunto(s)
Linfoma Anaplásico de Células Grandes , Neoplasias Cutáneas , Humanos , Linfoma Anaplásico de Células Grandes/complicaciones , Linfoma Anaplásico de Células Grandes/diagnóstico , Epiplón/patología , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/patologíaAsunto(s)
Artritis Reumatoide/complicaciones , Artritis Reumatoide/diagnóstico , Linfoma Cutáneo de Células T/complicaciones , Linfoma Cutáneo de Células T/diagnóstico , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/diagnóstico , Adulto , Artritis Reumatoide/terapia , Humanos , Linfoma Cutáneo de Células T/terapia , Masculino , Neoplasias Cutáneas/terapiaRESUMEN
Basal cell carcinoma (BCC) can be a component of a collision tumor in which the skin cancer is present at the same cutaneous site as either a benign tumor or a malignant neoplasm. However, BCC can also concurrently occur at the same skin location as a non-neoplastic cutaneous condition. These include autoimmune diseases (vitiligo), cutaneous disorders (Darier disease), dermal conditions (granuloma faciale), dermal depositions (amyloid, calcinosis cutis, cutaneous focal mucinosis, osteoma cutis, and tattoo), dermatitis, miscellaneous conditions (rhinophyma, sarcoidal reaction, and varicose veins), scars, surgical sites, systemic diseases (sarcoidosis), systemic infections (leischmaniasis, leprosy and lupus vulgaris), and ulcers. The relationship between the BCC and the coexisting non-neoplastic condition may be coincidental or possibly related to the development of the BCC; alternatively, the development of the BCC may be unrelated to the coexisting non-neoplastic conditions and secondary to either a Koebner isomorphic response or a Wolf isotopic response in an immunocompromised district of skin. This paper reviews several of the case reports and studies that describe the association of BCC with these non-neoplastic cutaneous conditions.
Asunto(s)
Carcinoma Basocelular/complicaciones , Enfermedades de la Piel/complicaciones , Neoplasias Cutáneas/complicaciones , HumanosAsunto(s)
Neoplasias Encefálicas/complicaciones , Glioblastoma/complicaciones , Enfermedades del Cabello/complicaciones , Pilomatrixoma/complicaciones , Neoplasias Cutáneas/complicaciones , Femenino , Enfermedades del Cabello/patología , Humanos , Neoplasias Primarias Múltiples/patología , Pilomatrixoma/patología , Neoplasias Cutáneas/patología , Adulto JovenAsunto(s)
Corticoesteroides/administración & dosificación , Linfocitos T CD4-Positivos , Interleucinas/administración & dosificación , Linfoma Cutáneo de Células T/tratamiento farmacológico , Trastornos Linfoproliferativos/tratamiento farmacológico , Neoplasias Cutáneas/tratamiento farmacológico , Adulto , Femenino , Humanos , Inyecciones Intralesiones/métodos , Linfoma Cutáneo de Células T/complicaciones , Linfoma Cutáneo de Células T/diagnóstico , Trastornos Linfoproliferativos/complicaciones , Trastornos Linfoproliferativos/diagnóstico , Nariz/efectos de los fármacos , Nariz/patología , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/diagnósticoAsunto(s)
Nevo Pigmentado/complicaciones , Nevo Pigmentado/diagnóstico por imagen , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/diagnóstico por imagen , Riñón Único/complicaciones , Riñón Único/diagnóstico por imagen , Niño , Cara/patología , Cabeza/patología , Humanos , Masculino , Cuello/patología , Tórax/patologíaAsunto(s)
Enfermedades Asintomáticas , Edema/diagnóstico , Hallux/patología , Osificación Heterotópica/diagnóstico , Neoplasias Cutáneas/diagnóstico , Neoplasias de los Tejidos Blandos/diagnóstico , Adolescente , Dermoscopía/métodos , Edema/etiología , Edema/cirugía , Hallux/cirugía , Humanos , Masculino , Osificación Heterotópica/complicaciones , Osificación Heterotópica/cirugía , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/cirugía , Neoplasias de los Tejidos Blandos/complicaciones , Neoplasias de los Tejidos Blandos/cirugíaRESUMEN
BACKGROUND: Tufted angioma is a rare benign lesion with vascular proliferation. AIM: To retrospectively analyze the clinicopathological manifestations and immunohistochemical features of tufted angioma. METHODS: Clinical and histopathological features of tufted angioma (n = 54) were evaluated and analyzed retrospectively in the Department of Dermatology, Xijing Hospital from 2003 to 2014. RESULTS: Clinically, tufted angioma usually presented as erythematous plaques and papules on the head and neck (n = 11), trunk (n = 21) and extremities (n = 22), mainly in children (n = 48), without gender difference (24 males and 30 females). A total of 45 cases showed solitary lesions and nine cases showed multiple lesions. Common symptoms included pain (n = 11), tenderness (n = 7), itching (n = 1), hypertrichosis (n = 7), hyperhidrosis (n = 6) and Kasabach-Merritt phenomenon (n = 1). Histopathologically, typical tufted angioma (n = 37) showed proliferation of endothelial cells in a so-called cannonball pattern, while in the early (n = 4) and regressed (n = 13) stages the tufted appearance was not prominent. The proliferated endothelial cells were diffusely positive for CD31 and Wilms tumor 1, focally positive for D2-40 and Prox1, and negative for Glut-1. LIMITATIONS: Our research was confined to patients of Chinese origin and our sample size was limited. CONCLUSIONS: Tufted angioma is a rare vascular neoplasm with diverse clinical manifestations and unique pathological features. It should be recognized as a vascular tumor with lymphatic differentiation. We emphasize the importance of considering tufted angioma in the differential diagnoses of any congenital or acquired vascular tumor.
Asunto(s)
Hemangioma/metabolismo , Hemangioma/patología , Neoplasias Cutáneas/metabolismo , Neoplasias Cutáneas/patología , Adolescente , Niño , Preescolar , China , Femenino , Hemangioma/complicaciones , Humanos , Lactante , Masculino , Estudios Retrospectivos , Neoplasias Cutáneas/complicaciones , Adulto JovenAsunto(s)
Vesícula/diagnóstico , Carcinoma Basocelular/diagnóstico , Hipotricosis/diagnóstico , Síndromes Paraneoplásicos/diagnóstico , Neoplasias Cutáneas/diagnóstico , Vesícula/etiología , Vesícula/terapia , Carcinoma Basocelular/complicaciones , Carcinoma Basocelular/terapia , Resultado Fatal , Humanos , Hipotricosis/complicaciones , Hipotricosis/terapia , Masculino , Persona de Mediana Edad , Síndromes Paraneoplásicos/complicaciones , Síndromes Paraneoplásicos/terapia , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/terapiaAsunto(s)
Carcinoma Basocelular/complicaciones , Intertrigo/complicaciones , Neoplasias Primarias Múltiples/complicaciones , Neoplasias Cutáneas/complicaciones , Anciano , Carcinoma Basocelular/patología , Carcinoma Basocelular/cirugía , Ingle , Humanos , Intertrigo/tratamiento farmacológico , Masculino , Neoplasias Primarias Múltiples/patología , Neoplasias Primarias Múltiples/cirugía , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/cirugíaRESUMEN
Cutaneous neoplasms frequently occur in leprosy, but there are few reports of the coexistence of leprosy and basal cell carcinoma in the same lesion. This case reports a 49-year-old male with an ulcerated plaque on the right lateral nasal wall, bright papules on the sternal region, and a blackened plaque on the right temporal region. The nasal and temporal lesions were diagnosed by histopathology as basal cell carcinoma and melanoma, respectively. The sternal lesions were excised with the repair of the "dog ear" which histopathological examination showed macrophages in the dermis parasitized with acid-fast bacilli, confirming the diagnosis of lepromatous leprosy with Fite-Faraco staining. This case report highlights the importance of referring the dog-ear specimen for histopathologic analysis.
Asunto(s)
Carcinoma Basocelular/complicaciones , Lepra Lepromatosa/complicaciones , Melanoma/complicaciones , Neoplasias Cutáneas/complicaciones , Biopsia , Carcinoma Basocelular/patología , Humanos , Lepra Lepromatosa/patología , Masculino , Melanoma/patología , Persona de Mediana Edad , Neoplasias Cutáneas/patologíaAsunto(s)
Ciclosporina/uso terapéutico , Inmunosupresores/uso terapéutico , Linfohistiocitosis Hemofagocítica/tratamiento farmacológico , Linfoma de Células T/tratamiento farmacológico , Paniculitis/tratamiento farmacológico , Neoplasias Cutáneas/tratamiento farmacológico , Adulto , Femenino , Humanos , Linfohistiocitosis Hemofagocítica/complicaciones , Linfohistiocitosis Hemofagocítica/patología , Linfoma de Células T/complicaciones , Linfoma de Células T/patología , Paniculitis/complicaciones , Paniculitis/patología , Neoplasias Cutáneas/complicacionesRESUMEN
Abstract Cutaneous neoplasms frequently occur in leprosy, but there are few reports of the coexistence of leprosy and basal cell carcinoma in the same lesion. This case reports a 49-year-old male with an ulcerated plaque on the right lateral nasal wall, bright papules on the sternal region, and a blackened plaque on the right temporal region. The nasal and temporal lesions were diagnosed by histopathology as basal cell carcinoma and melanoma, respectively. The sternal lesions were excised with the repair of the "dog ear" which histopathological examination showed macrophages in the dermis parasitized with acid-fast bacilli, confirming the diagnosis of lepromatous leprosy with Fite-Faraco staining. This case report highlights the importance of referring the dog-ear specimen for histopathologic analysis.
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cutáneas/complicaciones , Carcinoma Basocelular/complicaciones , Lepra Lepromatosa/complicaciones , Melanoma/complicaciones , Neoplasias Cutáneas/patología , Biopsia , Carcinoma Basocelular/patología , Lepra Lepromatosa/patología , Melanoma/patologíaRESUMEN
Basal cell carcinoma (BCC) is the most common malignant skin tumor which occurs more frequently over the sun exposed parts of body. Its adenoid variant is a rare histological subtype. We report a case of multiple adenoid basal cell carcinomas at unusual sites in a middle-aged male patient.
Asunto(s)
Carcinoma Basocelular/patología , Neoplasias Primarias Múltiples/patología , Neoplasias Cutáneas/patología , Úlcera Cutánea/etiología , Dorso , Carcinoma Basocelular/complicaciones , Carcinoma Basocelular/cirugía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Primarias Múltiples/complicaciones , Neoplasias Primarias Múltiples/cirugía , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/cirugía , Extremidad SuperiorRESUMEN
Subcutaneous panniculitis-like T cell lymphoma is a rare subtype of cutaneous lymphomas with distinct clinical, histological and immunophenotypic characteristics, as well as an indolent clinical course. Rarely, it may be complicated with hemophagocytic lymphohistiocytosis: a hyperinflammatory syndrome which, if not diagnosed early, carries a dismal outcome. In this article, we describe a case of subcutaneous panniculitis-like T cell lymphoma in a middle-aged female patient which was complicated with secondary hemophagocytic lymphohistiocytosis with a favorable outcome following etoposide-based therapy. The various histological mimics of subcutaneous panniculitis-like T cell lymphoma and the management options are also briefly discussed.